Patent: Methods & Compositions for Treating Pain

Physical pain can be curtailed with meds and beds but mental agony never goes away easily. Though the pills act fast on your pain their side effects need to be recorded and understood. Individuals suffering from pain find solace and peace only after treatment with opioid analgesics like morphine. The onset of such acute pain is sudden and short yet leaves a remarkable mark on the individual undergoing it-it does diminish pain but you also get to experience its side effects such as addiction, somnolescence, tolerance, respiratory depression and constipation frequently.
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Chronic pain management is a great public health concern as the use of opioids in pain management has significantly increased. We are not talking about a mild headache or a muscle pull that usually vanish with simple pain killers. In case of severe pain, the physician is bound to prescribe stronger pain meds-basically an opioid. When these are used as directed by the physician it helps in relieving acute pain (such as the aftereffects of a complicated surgery) but it does come with its heavy baggage-risks and complications when not used as per instructions. Opioids are drugs that work by interacting with opioid receptors in your cells and their effects are significantly due to decreased perception of pain, decreased reaction to pain and increased resistance to pain-the meds interact with receptors in the brain cells where these cells send signals that diminish pain and increased pleasure. This pleasure can sometimes become addictive and lead to frequent intake of the meds by the individual seeking solace in the pleasure resulting in an addiction. Also, at high doses the meds have the potential to diminish heart rate and breathing. Morphine, an opioid is made from the poppy plant and so are many other receptors such as Kadian or Contin.

The need of the hour is to come up with new treatments for alleviating pain without any unwanted side effects. We need one that identifies and develops new compounds and compositions that don’t cross the blood-brain barrier but minimize pain without touching the opioid receptors in the central nervous system. A new invention for treating pain patented here includes methods and compositions that comprise of dry powder and so. This invention facilitates pain management without the unwanted side effects such as respiratory depression, addiction, etc. and this makes it indispensable in today’s world as an excellent pain management technique. The composition here can be used for treating pain due to trauma, infection, HIV, small pox infection, some abnormality due to trauma, dental pain, central neuropathy, cancer, congenital defects, phantom limb pain, encephalitis, rheumatoid arthritis, fibromyalgia, back pain, multiple sclerosis, chronic pain, muscle pain, tendon pain, ligament pain, pain associated with diarrhea, irritable bowel syndrome, abdominal pain, chronic fatigue syndrome and spasms.

The analgesic composition can comprise of at least one peptide comprising an amino acid sequence of 3-20 amino acids in length, it can comprise of two amino acids that are phenylalanine groups or derivatives thereof. The composition administered to treat pain does its work without or with minimal side effects such as respiratory depression, gastrointestinal distress, addiction, nausea, tolerance, constipation and likewise. The invention is of immense use in practical life as the diseases and illnesses mentioned above are common ones that are frequently witnessed in today’s world. If you are looking for the exact composition of the compound patented here you can read through the entire patent published on June 4th 2015 whose details are available in any of the websites given below.

References
United States Patent & Trademark Office: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=2&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=98&f=G&l=50&co1=AND&d=PTXT&s1=nutrition&s2=%22weight+loss%22&OS=nutrition+AND+%22weight+loss%22&RS=nutrition+AND+%22weight+loss%22
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European Patent Office: https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20140417&DB=&locale=en_EP&CC=AU&NR=2012328885A1&KC=A1&ND=4
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World Intellectual Property Organization: https://patentscope.wipo.int/search/en/detail.jsf?docId=US133777752&tab=NATIONALBIBLIO&office=&prevFilter=&sortOption=Pub+Date+Desc&queryString=FP%3A%28leone-bay%29+andrea&recNum=36&maxRec=379